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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
14.24
Human Site:
S1190
Identified Species:
24.1
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
S1190
Q
K
M
Q
Q
K
K
S
Q
D
L
E
S
V
Q
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
S1190
Q
K
M
Q
Q
K
K
S
Q
D
L
E
S
V
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
L1190
Q
K
M
Q
Q
K
K
L
Q
D
L
E
S
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
S1190
Q
K
M
Q
Q
K
K
S
Q
D
V
E
S
V
Q
Rat
Rattus norvegicus
NP_001101888
2143
241191
S1190
Q
K
M
Q
Q
K
K
S
Q
D
V
E
A
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
P1201
K
M
Q
Q
Q
K
K
P
P
D
A
E
L
A
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
Q1185
R
S
K
M
R
K
T
Q
D
T
S
G
A
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
R1153
K
K
Q
P
V
K
R
R
S
V
Q
A
T
Q
L
Honey Bee
Apis mellifera
XP_393800
2028
231830
L1104
E
L
R
I
M
W
N
L
K
N
V
E
P
S
N
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
S779
F
S
T
I
I
N
S
S
G
Q
A
V
L
T
K
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
G764
D
G
P
L
Q
A
T
G
V
P
S
T
G
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
Q1105
N
R
F
Y
D
E
L
Q
T
D
V
Q
I
R
F
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
L898
V
L
Y
A
Q
E
T
L
I
S
C
T
L
N
T
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
L917
L
S
K
A
T
F
V
L
E
L
V
Q
E
S
E
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
86.6
N.A.
N.A.
40
N.A.
13.3
N.A.
13.3
6.6
6.6
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
N.A.
46.6
N.A.
33.3
N.A.
33.3
33.3
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
0
8
0
0
0
0
15
8
15
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
0
0
8
50
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
15
0
0
8
0
0
50
8
0
8
% E
% Phe:
8
0
8
0
0
8
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
8
0
0
0
0
0
8
8
0
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
15
8
0
0
0
8
0
0
0
8
0
0
% I
% Lys:
15
43
15
0
0
58
43
0
8
0
0
0
0
0
8
% K
% Leu:
8
15
0
8
0
0
8
29
0
8
22
0
22
8
8
% L
% Met:
0
8
36
8
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
8
0
0
8
0
0
0
8
8
% N
% Pro:
0
0
8
8
0
0
0
8
8
8
0
0
8
0
22
% P
% Gln:
36
0
15
43
58
0
0
15
36
8
8
15
0
8
36
% Q
% Arg:
8
8
8
0
8
0
8
8
0
0
0
0
0
8
0
% R
% Ser:
0
22
0
0
0
0
8
36
8
8
15
0
29
15
0
% S
% Thr:
0
0
8
0
8
0
22
0
8
8
0
15
8
8
8
% T
% Val:
8
0
0
0
8
0
8
0
8
8
36
8
0
43
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _